Antifungal Guidelines - By Patient Group

This page provides a link to some of the key guidelines about treatment of fungal disease and related topics.  Please note that this is not an exhaustive list.  If you know of other recently published guideslines that should be included, please let us know.

 

1.  Haematological Malignancy and/or Haematopoietic Stem Cell Transplant Recipients

1.1 Prophylaxis

Primary Antifungal Prophylaxis (ECIL5)

Tacke D et al. Primary prophylaxis of invasive fungal infections in patients with haematologic malignancies. 2014 update of the recommendations of the Infectious Diseases Working Party of the German Society for Haematology and Oncology.  Ann Hematol 2014;93:1449-1456

Fleming S  et al. Consensus guidelines for antifungal prophylaxis in haematological malignancy and haemopoietic stem cell transplantation, 2014.  Int Med J 2014;44:1283-1297

 

1.2  Empiric/Diagnostic Driven

Morrisey CO et al.  Consensus guidelines for the use of empiric and diagnostic-driven antifungal treatment strategies in haematological malignancy, 2014. Int Med J 2014;44:1298-1314

 

1.3  Treatment

Tissot F et al. ECIL-6 guidelines for the treatment of invasive candidiasis, aspergillosis and mucormycosis in leukaemia and haematopoietic stem cell transplant patients. Haematologica 2017;102(3):433-444

Alanio A et al. ECIL guidelines for the diagnosis of Pneumocystis jirovecii pneumonia in patients with haematological malignancies and stem cell transplant recipients. J Antimicrob Chemother 2016; 71(9): 2386-96.

Cordonnier C et al. Pneumocystis jirovecii pneumonia: still a concern in patients with haematological malignancies and stem cell transplant recipients. J Antimicrob Chemother 2016; 71(9): 2379-85.

Maertens J et al. ECIL guidelines for preventing Pneumocystis jirovecii pneumonia in patients with haematological malignancies and stem cell transplant recipients. J Antimicrob Chemother 2016; 71(9): 2397-404.

Maschmeyer G  et al. ECIL guidelines for treatment of Pneumocystis jirovecii pneumonia in non-HIV-infected haematology patients. J Antimicrob Chemother 2016; 71(9): 2405-13.

Groll A et al.  Fourth European Conference on Infections in Leukaemia (ECIL-4): guidelines for diagnosis, prevention, and treatment of invasive fungal diseases in paediatric patients with cancer or allogeneic haemopoietic stem-cell transplantation. The Lancet 2014;15(8)e327-340

Mousset S et al.  Treatment of invasive fungal infections in cancer patients—updated recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO). Ann Hematol. 2014;93:13-32

Blyth C et al.  Consensus guidelines for the treatment of invasive mould infections in haematological malignancy and haemopoietic stem cell transplantation. 2014. Int Med J 2014; 44:1333-1349

Chen S et al. Consensus guidelines for the treatment of yeast infections in the haematology, oncology and intensive care setting, 2014. Int Med J 2014;44:1315-1332

Skiada A et al. Diagnosis and treatment of mucormycosis in patients with hematological malignancies: guidelines from the 3rd European Conference on Infections in Leukemia (ECIL 3). Haematologica 2013; 98(4): 492-504.

Ullmann AJ et al. ESCMID guideline for the diagnosis and management of Candida diseases 2012: adults with haematological malignancies and after haematopoietic stem cell transplantation (HCT). Clin Micro Infect 2012;18 Supp 7:53-67

Maertens J et al. European guidelines for antifungal management in leukemia and hematopoietic stem cell transplant recipients: summary of the ECIL 3--2009 update. Bone Marrow Transplant 2011; 46(5): 709-18.

 

 

1.4  Therapeutic Drug Monitoring

Triazole Antifungal Therapeutic Drug Monitoring (ECIL6)

Chau MM et al.  Consensus guidelines for optimising antifungal drug delivery and monitoring to avoid toxicity and improve outcomes in patients with haematological malignancy, 2014. Int Med J 2014;44:1364-1388

 

1.5 Diagnosis

Marchetti O, Lamoth F, Mikulska M, et al. ECIL recommendations for the use of biological markers for the diagnosis of invasive fungal diseases in leukemic patients and hematopoietic SCT recipients. Bone Marrow Transplant 2012; 47(6): 846-54.

 

2.  Solid Organ Transplant Recipients

Gavalda J et al. Invasive fungal infections in solid organ transplant recipients. Clin Micro Infect 2014;20 (Suppl 7):27-48

 

3.  HIV Infection or AIDS

Lortholary O et al.  ESCMID* guideline for the diagnosis and management of Candida diseases 2012: patients with HIV infection or AIDS. Clin Micro Infect 2012;18 Supp 7:68-77

 

4. Neonates and children

Hope WW et al. ESCMID guideline for the diagnosis and management of Candida diseases 2012: prevention and management of invasive infections in neonates and children caused by Candida spp. Clin Micro Infect 2012;18 Supp 7:38-52

 

5.  Adult Pulmonary and Critical Care Patients

Limper A et al.  An Official American Thoracic Society Statement: Treatment of Fungal Infections in Adult Pulmonary and Critical Care Patients. Am J Respir Crit Care Med. 2011;183:96-128